Seroprevalence of Torch Infections in Bad Obstetrics History in HIV and Non-HIV Women in Solapur District of Maharashtra India

Bad obstetric history (BOH) implies previous unfavorable fetal outcome in terms of two or more consecutive spontaneous abortions, history of fetal death, intrauterine growth retardation, still birth, early neonatal death and/or congenital anomalies Kumari et al. [1]. Viral infections in pregnancy are a major cause of morbidity and mortality for both mother and fetus. Infections can occur in the neonate transplacentally, perinatally or postnatally. Cause of BOH may be genetic, hormonal, abnormal maternal immune response and maternal infection Turbadkar et al. [2]. TORCH infections in the mother are transmissible to fetus in the womb or during the birth process and cause a cluster of symptomatic birth defects. In mother they are inapparent or asymptomatic and hence difficult to diagnose clinically. Primary infections cause by TORCH infectionsToxoplasma gondii, rubella virus, CMV, HSV-1 and HSV-2 are the major cause of BOH McCabe & Remington [51]. Recurrent pregnancy wastage due to maternal infections transmissible in-utero at various state of gestation can be caused by wide array of organisms; to name a few would be TORCH infections, Listeria, and HIV.